The Benefits of Preimplantation Genetic Testing
Preimplantation genetic testing helps identify the risk of transmitting infections or genetic problems to babies. Testing allows for early intervention, giving patients the best chances for a healthy pregnancy and baby. At The Reproductive Medicine Group (RMG), we highly recommend these tests for all infertility patients.
Genetic screening identifies any significant health issues a patient may carry in their genes without knowing it. These conditions can affect the embryo’s implantation and growth, leading to pregnancy loss or the inability to become pregnant. At RMG, we conduct these screenings via a simple blood draw, which we then send to our partnering labs for analysis.
Screening can detect mutations associated with more than 175 serious conditions that fall into one of the following categories:
- Conditions where early treatment can make a difference (such as phenylketonuria (PKU))
- Conditions that cause intellectual disability (such as Fragile X syndrome)
- Conditions that shorten lifespan (such as Bloom Syndrome)
- Conditions where there are limited to no treatment options available (such as Tay-Sachs disease)
Preimplantation Genetic Testing for Aneuploidy (PGT-A)
Preimplantation Genetic Testing for Aneuploidy (PGT-A) is a genetic test used to screen embryos for chromosomal abnormalities. PGT-A involves the biopsy of a small number of cells from an embryo’s outer layer at the blastocyst stage, typically on the fifth or sixth day of development. Known as the trophoblast, the outer layer of the embryo later develops into the placenta; the part of the embryo that develops into the fetus (i.e., the inner cell mass) is not affected by the biopsy whatsoever.
Once biopsied, the cells are then analyzed to determine if the embryo has an abnormal number of chromosomes, a condition known as aneuploidy. Aneuploidy can lead to various genetic disorders, including conditions like Down syndrome, Turner syndrome, and others.
By identifying embryos with the correct number of chromosomes, PGT-A helps in selecting embryos that are more likely to result in a successful pregnancy and a healthy baby, while reducing the likelihood of implantation failure and miscarriage. PGT-A can be particularly beneficial for individuals and couples with a history of recurrent miscarriages, advanced maternal age, or previous unsuccessful IVF cycles.
Explore Preimplantation Genetic Testing in Florida
The Reproductive Medicine Group has many years of experience utilizing various forms of preimplantation genetic testing to help individuals and couples achieve their family-building dreams. With fertility clinic locations in North Tampa, South Tampa, Brandon, Clearwater, and Wesley Chapel, our expert team of fertility specialists is ready to answer all your questions and provide personalized fertility care. Schedule a consultation with The Reproductive Medicine Group.